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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 15.45
Human Site: Y125 Identified Species: 21.25
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 Y125 E R S P N E E Y T W E E D P L
Chimpanzee Pan troglodytes XP_507923 1056 119132 Y125 E R S P N E E Y T W E E D P L
Rhesus Macaque Macaca mulatta XP_001087644 853 96218
Dog Lupus familis XP_534964 1334 149091 Y407 E R S P N E E Y T W E E D P L
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 Y124 E R S P N E V Y T W E E D P L
Rat Rattus norvegicus O55165 796 89797
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 M112 S Q E H D P S M G V I P R V I
Frog Xenopus laevis P28025 1060 119314 F118 E R S S D E E F T W E Q D P L
Zebra Danio Brachydanio rerio NP_775368 955 106984 D90 S V V C P I L D E V I M G Y N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 S123 N E T A E L K S S W E D D S D
Honey Bee Apis mellifera XP_623508 706 80766
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46872 699 78679
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 E148 G A R K K N G E F P S D A G V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 A118 E C R R S K S A P C G G L P A
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 V161 D I N I L G D V Q S T D N L L
Red Bread Mold Neurospora crassa P48467 928 102392 D63 D M S C K Q S D I F D F S I K
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 0 100 N.A. 93.3 0 N.A. N.A. 0 73.3 0 N.A. 20 0 0 0
P-Site Similarity: 100 100 0 100 N.A. 93.3 0 N.A. N.A. 20 93.3 0 N.A. 46.6 0 0 0
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 0 N.A. N.A. 13.3 6.6 6.6
P-Site Similarity: 13.3 N.A. N.A. 26.6 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 6 0 0 0 6 0 0 0 0 6 0 6 % A
% Cys: 0 6 0 12 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 12 0 0 0 12 0 6 12 0 0 6 18 36 0 6 % D
% Glu: 36 6 6 0 6 30 24 6 6 0 36 24 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 6 6 6 0 6 0 0 0 % F
% Gly: 6 0 0 0 0 6 6 0 6 0 6 6 6 6 0 % G
% His: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 6 0 6 0 6 0 0 6 0 12 0 0 6 6 % I
% Lys: 0 0 0 6 12 6 6 0 0 0 0 0 0 0 6 % K
% Leu: 0 0 0 0 6 6 6 0 0 0 0 0 6 6 36 % L
% Met: 0 6 0 0 0 0 0 6 0 0 0 6 0 0 0 % M
% Asn: 6 0 6 0 24 6 0 0 0 0 0 0 6 0 6 % N
% Pro: 0 0 0 24 6 6 0 0 6 6 0 6 0 36 0 % P
% Gln: 0 6 0 0 0 6 0 0 6 0 0 6 0 0 0 % Q
% Arg: 0 30 12 6 0 0 0 0 0 0 0 0 6 0 0 % R
% Ser: 12 0 36 6 6 0 18 6 6 6 6 0 6 6 0 % S
% Thr: 0 0 6 0 0 0 0 0 30 0 6 0 0 0 0 % T
% Val: 0 6 6 0 0 0 6 6 0 12 0 0 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 24 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _